The two following links came up as promising ones. So I Googled the search-term “can i remove $PatchCache$”.
This was made more important since I had less than 10% free space, making even defragmenting using “ Defraggler” not optimal.
In one my machines, the C:\ drive (actually a partition on a larger drive) where Windows directory was located had only 10 GB total allocation (since it was a Windows XP SP3 machine and 8 years old), I needed to recover some space in the c:\ partition.